Application Review Process
The OSU IRB Office, located in the Office of University Research Compliance (URC)
coordinates the receipt and review of all IRB applications. The URC staff will pre-review
the application to ensure that all of the necessary materials are provided for IRB
review. If additional information is needed before review can begin, you will be contacted
via the IRBManager system. The application is assigned a unique number that is used
to track it through the system.
Ensuring responsible conduct of research must be an on-going process. DHHS regulations
at [45 CFR 46.109(e)] require the continuing review of human subjects research by the IRB at intervals
appropriate to the degree of risk.
The goals of this process are to re-evaluate the acceptability of the risk/benefit
ratio and subject safeguards, and to confirm that the approved protocol has been followed.
Any research activity initially reviewed and approved by the OSU IRB is subject to